Results: The mean age of the entire population was 63.6 years (range 35 to 86). Abnormal digital rectal examination findings were present in 33.4% of the patients. The mean and median values of PSA and cPSA were significantly higher and the F/T PSA ratio was lower in patients with prostate cancer.

Over the past years, the assessment of equimolarity has been typically performed by the characterization of the recovery of IS 96/670, consisting of 90% PSA-ACT and 10% PSA free form, by marketed PSA assays.
In addition, previous attempts to measure complexed PSA (PSA±ACT: PSA bound to a-1-antichymotrypsin) have been limited to the high cross reactivity of the monoclonal antibodies to other ACT
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    • complexed psa vs free psa